PEIpro?
Viral vector for Gene & Cell Therapy
Large-scale virus Production
Optimized PEI-based transfection reagent for scalable virus production
Superior viral titers compared to other commercial PEIs and Calcium Phosphate
Suitable for Process Development of large-scale virus production
Reliable and secure supply
Overview
Specifications
|
Reagent |
PEIpro® |
|
Concentration |
1 mg/mL |
|
Molecule delivered |
Plasmid DNA and co-delivery of several plasmid DNA |
|
Applications |
Large-scale virus production |
|
Virus types |
Mainly adenovirus, Adeno-Associated Viruses (AAV), Lentivirus, influenza virus, retrovirus, Virus-like particles (VLP) |
|
Cell types |
Mammalian producer cell lines (HEK-293, HEK-293 derivatives, BHK, VERO cell lines, virus-specific packaging cell lines. |
|
Number of transfections |
100 mL of PEIpro® transfection reagent is sufficient to transfect on average 50 L of cell culture |
|
Storage |
5 ± 3 °C, 3 years from manufacturing date |
|
Provided with |
Protocol |
Summary
PEIpro® transfection reagent is the leading chemical-based DNA transfection reagent that offers flexibility and scalability to develop a robust and sustainable Process Development for viral vector production. PEIpro® benefits from extensive research development in PEI polymer chemistry and formulation to achieve highest transfection efficiency in both adherent and suspension cell culture systems. Protocols established with PEIpro® during Process Development are directly implementable for large-scale manufacturing of preclinical and clinical batches of viral vectors with the higher quality grades of PEIpro®: PEIpro®-HQ and PEIpro®-GMP.
Ordering information
|
Reference Number |
Amount of reagent |
|
115-0015 |
1.5 ml |
|
115-010 |
10 ml |
|
115-100 |
100 ml |
|
115-01L |
1 L |
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RTU (Ready-to-Use) 速溶颗粒
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